Biphasic Effects of THC on Anxiety
Low doses of THC tend to reduce anxiety while higher doses tend to provoke it — a dose-response curve with rea...
CBD and Antipsychotic Effects
What the evidence actually says about cannabidiol as a treatment for psychosis and schizophrenia, separated fr...
CBD and Anxiety
What the evidence actually says about cannabidiol for anxiety disorders, panic, social anxiety, and everyday s...
CBD and Cyclosporine: Interaction Risks
Cannabidiol can raise cyclosporine blood levels through shared liver enzymes, creating a real but understudied...
CBD and Dravet Syndrome
Pharmaceutical-grade cannabidiol is one of the few cannabis-derived treatments with strong randomized trial ev...
CBD and Lennox-Gastaut Syndrome
Pharmaceutical-grade cannabidiol reduces drop seizures in Lennox-Gastaut syndrome, with strong randomized tria...
CBD and Sleep
What the evidence actually says about cannabidiol for insomnia, sleep quality, and sleep disorders.
CBN and Sleep
What the evidence actually says about cannabinol as a sleep aid, separating lab data from marketing claims.
Cannabinoids and Apoptosis Research
What the evidence actually says about cannabinoids triggering programmed cell death in cancer and other diseas...
Cannabis Hyperemesis Syndrome (CHS)
A paradoxical syndrome of cyclic vomiting in chronic cannabis users that resolves only with cessation.
Cannabis Smoke vs Tobacco Smoke
A look at what the research actually shows when comparing the health effects of smoked cannabis with smoked to...
Cannabis Tolerance and Sleep Effects
What the evidence actually says about cannabis, sleep, and how quickly your body adapts to its sedating effect...
Cannabis Use Disorder
A real DSM-5 diagnosis affecting roughly 1 in 5 regular users, with modest but growing evidence on what actual...
Cannabis Use With Autoimmune Therapy
What the evidence actually says about combining cannabis with biologics, DMARDs, and other immune-modulating d...
Cannabis Use in Adolescence and Psychosis
What the evidence actually says about whether teen cannabis use causes psychotic disorders, and what's still u...
Cannabis Use in Older Adults
What the evidence says about cannabis for people over 65, including pain, sleep, dementia, and drug interactio...
Cannabis Use in Pediatric Autism Research
What the evidence actually says about cannabidiol and whole-plant cannabis extracts for autistic children, sep...
Cannabis Vaporization and Respiratory Effects
What the evidence actually says about inhaling vaporized cannabis versus smoking it, and what it does to your...
Cannabis Withdrawal and Sleep Disruption
Insomnia is the most reliable symptom when regular cannabis users quit, and it's the one most likely to push p...
Cannabis and ALS (Amyotrophic Lateral Sclerosis)
What the evidence actually says about cannabis for ALS symptoms, disease modification, and quality of life.
Cannabis and Acne
What the evidence actually says about cannabinoids, CBD, and topical hemp products for acne vulgaris.
Cannabis and Alzheimer's Disease
What the evidence actually says about cannabinoids for Alzheimer's prevention, treatment, and behavioral sympt...
Cannabis and Appetite Stimulation
What the evidence actually says about cannabis, THC, and 'the munchies' as a treatment for appetite loss and w...
Cannabis and Arthritis Pain
What the evidence actually says about using cannabis for osteoarthritis, rheumatoid arthritis, and related joi...