Cannabis and the Developing Brain
What the evidence actually says about cannabis use during adolescence and young adulthood, separated from both...
Cannabis and the Gateway Drug Hypothesis
What the evidence actually says about whether cannabis use leads to harder drug use later in life.
Cannabis for Chronic Diarrhea
What the evidence actually says about using cannabis, THC, and CBD to manage chronic diarrhea from various cau...
Cannabis for Hot Flashes
What the evidence actually says about using cannabis to manage menopausal vasomotor symptoms — and what it doe...
Cannabis for IBS-C (Constipation-Predominant Irritable Bowel Syndrome)
The honest state of evidence on whether cannabis helps constipation-predominant IBS, and where it probably mak...
Cannabis for Jet Lag
There's no direct evidence cannabis treats jet lag, and its effects on sleep architecture may make circadian r...
Cannabis for Muscle Cramps
What the evidence actually says about using cannabis for muscle cramps in MS, ALS, dystonia, and ordinary leg...
Cannabis for Tremor
An honest look at what cannabis can and can't do for essential tremor, Parkinson's tremor, and other movement...
Cannabis in Palliative Care
What the evidence actually shows about cannabis for symptom relief at the end of life — and where the science...
Cannabis in Pediatric Epilepsy
Pharmaceutical CBD has real, replicated evidence for specific rare epilepsies; most other cannabis claims in k...
Cannabis-Induced Anxiety
When the thing you used to calm down is the thing making you panic — what we actually know about cannabis trig...
Cannabis-Induced Psychosis
What we actually know about cannabis triggering psychotic symptoms, who's at risk, and how it differs from sch...
Cesamet (Nabilone)
A synthetic THC analog prescribed for chemotherapy-induced nausea, with limited but real evidence for a few ot...
Daily Cannabis Use: Health Effects
What the evidence actually says about using cannabis every day, from cognition and lungs to dependence and car...
Epidiolex (Cannabidiol)
The first FDA-approved cannabis-derived drug, a purified CBD oral solution used for specific rare seizure diso...
FAAH Enzyme
The enzyme that breaks down your body's own cannabinoids, and why drug developers keep trying — and mostly fai...
First-Pass Metabolism of THC
Why swallowing THC hits differently than smoking it, and why edibles are so easy to overdo.
High-Potency THC and Psychosis Risk
What the evidence actually says about whether strong cannabis causes psychotic disorders, who is most vulnerab...
Medical Cannabis for Autoimmune Conditions
A sober look at what cannabis can and cannot do for autoimmune disease, from lupus to MS to rheumatoid arthrit...
Medical Cannabis for Cancer Patients
What the evidence actually shows for cancer symptoms, treatment side effects, and the persistent claim that ca...
Risks of Cannabis Use in Adolescents
What the evidence actually says about teenage cannabis use, separating well-replicated harms from media panic...
Smoking Cannabis and Lung Health
What decades of research actually say about how smoked cannabis affects your lungs, and where the science is s...
Sublingual Cannabis Pharmacokinetics
How cannabis taken under the tongue actually gets into your blood, what the evidence shows, and where the mark...
THC Dose and Anxiety
Low doses of THC tend to reduce anxiety in lab studies; higher doses reliably increase it. The threshold is na...