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Also known as: Four 20 Pharma GmbH · Four 20 Pharma · 420NATURAL

420 Pharma

Paderborn-based medical cannabis manufacturer, importer and wholesaler behind the 420NATURAL brand, wholly owned by Curaleaf since 2026.

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420 Pharma is the trading name of Four 20 Pharma GmbH, a Paderborn company that makes, imports and wholesales medical cannabis for German pharmacies under the 420NATURAL brand. It is no longer independent: US multistate operator Curaleaf bought a majority in 2022 and the rest in April 2026. The public record covers ownership and licences well, but not product quality. Batch data, strains and prices change often, so patients and pharmacists should check the current product sheet rather than marketing claims.

What it is

420 Pharma is the trading name of Four 20 Pharma GmbH, registered at Friedrich-List-Straße 67 in Paderborn, Germany [5] Strong evidence. The company describes itself as a certified manufacturer, importer and wholesaler of medical cannabis flowers and full-spectrum extracts [11], and Curaleaf describes it as a fully EU-GMP and GDP licensed producer and distributor [6] Weak / limited.

It operates in Germany's prescription channel: flower and extracts reach patients only through pharmacies, on a doctor's prescription [2]. Since the Medical Cannabis Act (MedCanG) took effect on 1 April 2024, medical cannabis is no longer classed as a narcotic in Germany but remains prescription-only [9] Strong evidence.

Ownership

The Bundestag lobby register lists Tino-Peter Haack and Juan Pablo Martinez as managing directors [5]. The company has been registered as a lobbying organisation since October 2022, with interests in cannabis law, telemedicine for medical cannabis and reducing bureaucracy [5].

Curaleaf supplies flower from its own production in Portugal and Canada, and Four 20 Pharma distributes it alongside its own products [6] Weak / limited. For Curaleaf's wider European business see Curaleaf International.

Products and brands

Weedpedia does not list individual strains, potencies or prices: they change frequently and are best read from the pharmacy's current product information. Product choice is a clinical decision between doctor, patient and pharmacist.

Size and market position

Curaleaf reported in 2026 that Four 20 Pharma employs about 110 people and called its brand one of Germany's most trusted medical cannabis brands [6]. That is the parent company's own description; independent market-share data is not public No data.

The company is one of dozens of producers and importers serving German pharmacies [1]. We found no regulatory enforcement actions or investigative reporting specifically about it as of October 2026 No data. That is not proof of a clean record; it may simply reflect a low public profile.

Regulatory outlook

German medical cannabis rules are in flux. In October 2025 the federal cabinet approved a bill that would require an in-person doctor's consultation before prescribing and ban mail-order delivery of cannabis flowers [10] Strong evidence. A Bundestag vote had been expected in early 2026; check the current status before relying on it. The outcome affects every supplier in this market, including Four 20 Pharma.

How to verify claims

Before relying on any claim about this company or its products, including its own marketing:

Sources

  1. Peer-reviewed Schmidt-Wolf G, Cremer-Schaeffer P. (2021). 'Drei Jahre Cannabis als Medizin – Begleiterhebung nach § 31 Absatz 6 des Fünften Buches Sozialgesetzbuch.' Bundesgesundheitsblatt, 64, 368–377.
  2. Government Bundesministerium für Gesundheit. '"Cannabis als Medizin" – Fragen und Antworten zum Gesetz.' Accessed October 2026.
  3. Government Bundesanzeiger Verlag. 'Unternehmensregister / Handelsregister.' Official German commercial register portal.
  4. Government European Medicines Agency. 'EudraGMDP – Community database on manufacturing, import and wholesale-distribution authorisations and GMP / GDP certificates.'
  5. Government Lobbyregister des Deutschen Bundestages. Entry R005341: Four 20 Pharma GmbH, Friedrich-List-Str. 67, 33100 Paderborn. First registered 13 October 2022.
  6. Reported Curaleaf Holdings (EQS News / PR Newswire). 'Curaleaf Completes Buyout of Remaining Stake in Germany's Four 20 Pharma.' 30 April 2026.
  7. Reported Curaleaf Holdings (PR Newswire). 'Curaleaf Completes Majority Stake Acquisition of Germany's Four 20 Pharma.' 19 September 2022.
  8. Reported Apotheke Adhoc. 'Four 20 Pharma GmbH tritt mit 420 Natural in den tschechischen Markt ein.' 5 November 2021.
  9. Government Gesetz zur Versorgung mit Cannabis zu medizinischen und medizinisch-wissenschaftlichen Zwecken (Medizinal-Cannabisgesetz – MedCanG), BGBl. 2024 I Nr. 109, in force 1 April 2024.
  10. Reported Dölger, Cornelia. 'Mailaktion gegen Cannabis-Versandverbot.' Pharmazeutische Zeitung, 17 November 2025.
  11. Practitioner Four 20 Pharma GmbH. Company website: 'Der Spezialist für Medizinalcannabis'. Accessed October 2026.

How this page was made

Generation history

Oct 29, 2026
Editorial review
Jun 8, 2026
Fact-check pass — raised 2 flags
Jun 8, 2026
Initial draft

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