Growing Cannabis in Mississippi

Cannabis cultivation has been a topic of considerable interest and debate in various regions worldwide. In Mississippi, the legalization of medical marijuana and subsequent changes to cultivation regulations have piqued the interest of enthusiasts and potential cultivators. This article aims to provide a comprehensive overview of the legal, environmental, and best-practice aspects of cannabis cultivation in Mississippi.

Historical and Legal Context

Mississippi, like many other U.S. states, has a tumultuous history with cannabis. The plant, once criminalized, has seen shifts in perception and legality over the years.

Historical Legality

Until the early 21st century, the cultivation, possession, and sale of cannabis in Mississippi was illegal. The state’s strict stance on drugs meant that many individuals found in possession or cultivating even small amounts faced harsh penalties.

Medical Marijuana Legalization

In November 2020, Mississippians voted in favor of Initiative 65, which sought to allow qualified patients with debilitating medical conditions to use medical marijuana. This change marked a significant turning point for cannabis cultivation in the state.

Current Regulations

As of the last update in this article, the Mississippi Department of Health regulates the medical marijuana program. This body provides licenses and sets guidelines for the cultivation, processing, testing, and sale of medical cannabis in Mississippi. Potential growers must apply for cultivation licenses, and there are strict guidelines on plant count, security measures, and reporting to ensure compliance.

Environmental Factors and Cultivation Challenges

Mississippi’s subtropical climate, characterized by hot, humid summers and mild winters, presents both opportunities and challenges for cannabis cultivators.


While cannabis generally thrives in temperatures between 68°F and 77°F, Mississippi’s summer temperatures can soar, potentially stressing plants. It is crucial for growers to monitor and possibly adjust conditions, especially if growing outdoors.


High humidity levels, a hallmark of Mississippi’s climate, can be problematic for cannabis cultivation. Elevated humidity can encourage the growth of mold and mildew on cannabis plants, which can reduce yield and quality.

Pests and Diseases

The warm and humid climate of Mississippi is conducive to a variety of pests and diseases that can threaten cannabis crops. Regular monitoring and integrated pest management practices are essential to maintain plant health.

Best Practices for Cannabis Cultivation in Mississippi

Indoor vs. Outdoor Cultivation

Given the state’s challenging climate, many growers opt for indoor cultivation, where environmental conditions can be controlled. While indoor cultivation may be more costly due to the need for equipment and energy, it offers more predictable results. Those who choose outdoor cultivation in Mississippi often utilize greenhouses to protect their crops from excessive moisture and pests.

Strain Selection

Not all cannabis strains are created equal, especially when considering regional growth. For Mississippi, cultivators may want to consider strains known for their resistance to mold and pests.

Regular Monitoring

With the state’s propensity for high humidity and pest-related issues, regular monitoring is crucial. Growers should inspect their plants daily, looking out for signs of diseases or pest infestations. Catching these issues early can mean the difference between a successful harvest and a lost crop.

Soil and Nutrition

Mississippi’s soil can vary in quality, but in many areas, it’s fertile and well-draining, suitable for cannabis cultivation. Regular soil testing can help growers determine if any amendments are needed. Additionally, providing cannabis plants with the right nutrients at the right times can optimize growth and yield.


Growing cannabis in Mississippi, while challenging due to its subtropical climate, is feasible with the right practices, strain selection, and regular monitoring. As the state continues to navigate the evolving landscape of cannabis legalization and cultivation, growers armed with knowledge and best practices are well-positioned to produce quality crops. As with any agricultural endeavor, continuous learning and adaptation to the specific challenges of the region will be the key to success for Mississippi’s budding cannabis industry.