Cannabis Strains in Missouri

Missouri, located in the central United States, is a state with a complex history regarding cannabis. With changing regulations, the state’s residents have gradually been introduced to a variety of cannabis strains, each with its unique properties. This article delves into the historical background, the most popular strains in Missouri, the medical cannabis movement, and the current legal landscape surrounding cannabis cultivation in the state.

Historical Background

Cannabis has been cultivated and utilized for centuries across many cultures. However, in the context of the United States, it was stigmatized and prohibited for much of the 20th century. Missouri, like many other states, implemented strict anti-cannabis laws during the 1930s, which effectively criminalized the possession, sale, and cultivation of the plant.

It wasn’t until the early 21st century that there was a shift in public perception and policy towards cannabis, not just in Missouri but across the nation. This change paved the way for the legalization of medical cannabis in Missouri in 2018, which has since opened the doors to a more detailed exploration of strains tailored for the state’s population.

Popular Cannabis Strains in Missouri

As the medical cannabis industry evolved, several strains became particularly popular among Missouri’s residents. While the choice of strain often depends on individual preferences and medical needs, some notable strains that have gained traction include:

  • Blue Dream: A sativa-dominant hybrid, Blue Dream is prized for its balanced effects that combine full-body relaxation with gentle cerebral invigoration. Patients report relief from pain, depression, and nausea.
  • OG Kush: Recognized for its earthy pine and sour lemon scent with woody undertones, this hybrid strain provides a strong euphoric feeling, making it popular among those suffering from stress, anxiety, and pain.
  • Girl Scout Cookies (GSC): This hybrid strain is known for its potent effects that deliver a mix of euphoria and relaxation. It’s often chosen to treat pain, appetite loss, and nausea.
  • Gorilla Glue #4: Often referred to as GG4, this potent hybrid strain is celebrated for its heavy-handed euphoria and relaxation, making it ideal for those with chronic pain and sleep disorders.
  • Pineapple Express: A sativa-dominant strain, Pineapple Express is popular for its mild, uplifting effects and sweet tropical flavors. It’s often chosen by patients dealing with chronic fatigue and mood disorders.

The Medical Cannabis Movement

Missouri’s Amendment 2, passed in 2018, legalized medical marijuana, allowing patients with qualifying conditions to access cannabis for therapeutic purposes. This movement was propelled by the growing body of evidence supporting the medicinal benefits of cannabis for conditions like chronic pain, epilepsy, glaucoma, and several others.

With the passage of this amendment, the state established a regulatory framework that oversees the cultivation, processing, and dispensing of medical cannabis. This formalized system also led to a surge in interest and research into the specific strains that would best serve Missouri’s patient population. The medical cannabis movement in Missouri is a testament to the shifting perceptions of cannabis and its potential therapeutic benefits.

Cultivation and Legality

In light of the medical cannabis legislation, Missouri has set up strict guidelines regarding the cultivation of cannabis. Licensed cultivation facilities are mandated to follow rigorous security, tracking, and quality assurance protocols to ensure patient safety.

While medical cannabis is legal, recreational use remains prohibited in Missouri as of the last update in 2021. However, in cities like St. Louis and Kansas City, the possession of small amounts of cannabis has been decriminalized, highlighting a shift towards a more lenient approach.

Those interested in growing cannabis in Missouri, either for personal medical use or as part of the state’s burgeoning cannabis industry, must remain cognizant of the evolving legal landscape and ensure they adhere strictly to state regulations.


The emergence and popularity of various cannabis strains in Missouri is closely tied to the state’s evolving legal and cultural landscape. As the state continues to refine its approach to cannabis, it is likely that the range of available strains and their uses will expand, offering Missouri residents a broader spectrum of choices to meet their medical and therapeutic needs.